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Human serum albumin complexed with myristate, azapropazone and indomethacin

X-ray diffraction
2.4Å resolution
PDB entry 2bxk coloured by chain, front view.
PDB entry 2bxk coloured by chain, side view.
PDB entry 2bxk coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Albumin
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Multimeric state: monomeric
Accessible surface area: 27486.18 Å2
Buried surface area: 5855.88 Å2
Dissociation area: 619.23 Å2
Dissociation energy (ΔGdiss): -15.33 kcal/mol
Dissociation entropy (TΔSdiss): 5.17 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136176

Macromolecules

Albumin
Chain: A
Length: 585 amino acids
Theoretical weight: 66.54 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02768 (Residues: 25-609; Coverage: 99%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Pfam: Serum albumin family
InterPro:
CATH: Serum Albumin; Chain A, Domain 1
SCOP: Serum albumin-like
Albumin in PDB entry 2bxk, assembly 1, front view.
Albumin in PDB entry 2bxk, assembly 1, side view.
Albumin in PDB entry 2bxk, assembly 1, top view.
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