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Interactions of protective signalling factor with chitin-like polysaccharide: Crystal structure of the complex between signalling protein from sheep (SPS-40) and a hexasaccharide at 2.5A resolution

X-ray diffraction
2.54Å resolution
PDB entry 2dsv coloured by chain, front view.
PDB entry 2dsv coloured by chain, side view.
PDB entry 2dsv coloured by chain, top view.
Source organism: Ovis aries
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Chitinase-3-like protein 1
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Multimeric state: monomeric
Accessible surface area: 15514.72 Å2
Buried surface area: 3540.48 Å2
Dissociation area: 1,032.44 Å2
Dissociation energy (ΔGdiss): -22.34 kcal/mol
Dissociation entropy (TΔSdiss): 7.73 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-180381

Macromolecules

Chitinase-3-like protein 1
Chain: A
Length: 361 amino acids
Theoretical weight: 40.61 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: Q6TMG6 (Residues: 1-361; Coverage: 100%)
Gene name: CHI3L1
Pfam: Glycosyl hydrolases family 18
InterPro:
CATH:
SCOP:
Chitinase-3-like protein 1 in PDB entry 2dsv, assembly 1, front view.
Chitinase-3-like protein 1 in PDB entry 2dsv, assembly 1, side view.
Chitinase-3-like protein 1 in PDB entry 2dsv, assembly 1, top view.
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