› › Structure analysis

Crystal Structure of Gyp1 TBC domain in complex with Rab33 GTPase bound to GDP and AlF3

X-ray diffraction
2.26Å resolution
PDB entry 2g77 coloured by chain, front view.
PDB entry 2g77 coloured by chain, side view.
PDB entry 2g77 coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: GTPase-activating protein GYP1 and Ras-related protein Rab-33B
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 21907.67 Å2
Buried surface area: 3741.35 Å2
Dissociation area: 1,332.44 Å2
Dissociation energy (ΔGdiss): 1.56 kcal/mol
Dissociation entropy (TΔSdiss): 12.71 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-128722

Macromolecules

GTPase-activating protein GYP1
Chain: A
Length: 410 amino acids
Theoretical weight: 48.16 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08484 (Residues: 244-637; Coverage: 62%)
Gene names: GYP1, YOR070C, YOR29-21
Pfam: Rab-GTPase-TBC domain
InterPro:
CATH: Ypt/Rab-GAP domain of gyp1p, domain 3
SCOP: Ypt/Rab-GAP domain of gyp1p
GTPase-activating protein GYP1 in PDB entry 2g77, assembly 1, front view.
GTPase-activating protein GYP1 in PDB entry 2g77, assembly 1, side view.
GTPase-activating protein GYP1 in PDB entry 2g77, assembly 1, top view.
Molecule details ›

Search similar proteins

Ras-related protein Rab-33B
Chain: B
Length: 198 amino acids
Theoretical weight: 22.55 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35963 (Residues: 14-202; Coverage: 83%)
Gene name: Rab33b
Pfam: Ras family
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases
SCOP: G proteins
Ras-related protein Rab-33B in PDB entry 2g77, assembly 1, front view.
Ras-related protein Rab-33B in PDB entry 2g77, assembly 1, side view.
Ras-related protein Rab-33B in PDB entry 2g77, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links