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Crystal structure of UTR4 protein (Unknown transcript 4 protein) (yel038w) from Saccharomyces cerevisiae at 2.28 A resolution

X-ray diffraction
2.28Å resolution
PDB entry 2g80 coloured by chain, front view.
PDB entry 2g80 coloured by chain, side view.
PDB entry 2g80 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Enolase-phosphatase E1
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Multimeric state: monomeric
Accessible surface area: 11256.79 Å2
Buried surface area: 411.86 Å2
Dissociation area: 154.27 Å2
Dissociation energy (ΔGdiss): -5.58 kcal/mol
Dissociation entropy (TΔSdiss): 1.67 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-542822
Assembly 2
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Assembly Name: Enolase-phosphatase E1
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Multimeric state: monomeric
Accessible surface area: 11282.29 Å2
Buried surface area: 103.65 Å2
Dissociation area: 51.82 Å2
Dissociation energy (ΔGdiss): 9.62 kcal/mol
Dissociation entropy (TΔSdiss): -1.46 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-542822
Assembly 3
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Assembly Name: Enolase-phosphatase E1
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Multimeric state: monomeric
Accessible surface area: 11337.63 Å2
Buried surface area: 373.95 Å2
Dissociation area: 95.88 Å2
Dissociation energy (ΔGdiss): 0.35 kcal/mol
Dissociation entropy (TΔSdiss): 0.91 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-542822
Assembly 4
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Assembly Name: Enolase-phosphatase E1
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Multimeric state: monomeric
Accessible surface area: 11251.31 Å2
Buried surface area: 454.72 Å2
Dissociation area: 124.34 Å2
Dissociation energy (ΔGdiss): 0.17 kcal/mol
Dissociation entropy (TΔSdiss): 0.91 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-542822

Macromolecules

Enolase-phosphatase E1
Chains: A, B, C, D
Length: 253 amino acids
Theoretical weight: 28.23 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P32626 (Residues: 1-227; Coverage: 100%)
Gene names: SYGP-ORF20, UTR4, YEL038W
Pfam: haloacid dehalogenase-like hydrolase
InterPro:
CATH:
SCOP: Enolase-phosphatase E1
Enolase-phosphatase E1 in PDB entry 2g80, assembly 1, front view.
Enolase-phosphatase E1 in PDB entry 2g80, assembly 1, side view.
Enolase-phosphatase E1 in PDB entry 2g80, assembly 1, top view.
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