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The crystal structure of the RNase A- 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine complex

X-ray diffraction
1.7Å resolution
PDB entry 2g8r coloured by chain, front view.
PDB entry 2g8r coloured by chain, side view.
PDB entry 2g8r coloured by chain, top view.
Source organism: Bos taurus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Ribonuclease pancreatic
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Multimeric state: monomeric
Accessible surface area: 6973.65 Å2
Buried surface area: 971.29 Å2
Dissociation area: 244.75 Å2
Dissociation energy (ΔGdiss): -6.93 kcal/mol
Dissociation entropy (TΔSdiss): 4.43 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158390
Assembly 2
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Assembly Name: Ribonuclease pancreatic
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Multimeric state: monomeric
Accessible surface area: 6977.33 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158390

Macromolecules

Ribonuclease pancreatic
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Pfam: Pancreatic ribonuclease
InterPro:
CATH: Ribonuclease A-like domain
SCOP: Ribonuclease A-like
Ribonuclease pancreatic in PDB entry 2g8r, assembly 1, front view.
Ribonuclease pancreatic in PDB entry 2g8r, assembly 1, side view.
Ribonuclease pancreatic in PDB entry 2g8r, assembly 1, top view.
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