Structure analysis

Interrupting the Hydrogen Bonding Network at the Active Site of Human Manganese Superoxide Dismutase

X-ray diffraction
2.3Å resolution
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer
Accessible surface area: 31072.93 Å2
Buried surface area: 8320.02 Å2
Dissociation area: 2,235.56 Å2
Dissociation energy (ΔGdiss): 9.95 kcal/mol
Dissociation entropy (TΔSdiss): 14.56 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-137485

Macromolecules

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