Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA
Source organism:
Escherichia coli
Biochemical function:
toxin sequestering activity
Biological process: negative regulation of DNA-templated transcription
Cellular component: toxin-antitoxin complex
Biological process: negative regulation of DNA-templated transcription
Cellular component: toxin-antitoxin complex
Protein family (Pfam)![The deposited structure of PDB entry 2h3a contains 2 copies of Pfam domain PF07362 (Post-segregation antitoxin CcdA) in Antitoxin CcdA. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/2h3a_3_A_Pfam_PF07362_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2h3a</span> contains 2 copies of Pfam domain <span class='highlight'>PF07362 (Post-segregation antitoxin CcdA)</span> in <span class='highlight'>Antitoxin CcdA</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
InterPro annotation
CATH domain![The deposited structure of PDB entry 2h3a contains 1 copy of CATH domain 1.10.1220.80 (Arc Repressor Mutant) in Antitoxin CcdA. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/2h3a_3_A_CATH_1.10.1220.80_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2h3a</span> contains 1 copy of CATH domain <span class='highlight'>1.10.1220.80 (Arc Repressor Mutant)</span> in <span class='highlight'>Antitoxin CcdA</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")