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Epstein Barr Virus Major Envelope Glycoprotein

X-ray diffraction
3.5Å resolution
PDB entry 2h6o coloured by chain, front view.
PDB entry 2h6o coloured by chain, side view.
PDB entry 2h6o coloured by chain, top view.
Source organism: Human gammaherpesvirus 4
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Major outer envelope glycoprotein gp350
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Multimeric state: monomeric
Accessible surface area: 37238.47 Å2
Buried surface area: 16158.97 Å2
Dissociation area: 55.21 Å2
Dissociation energy (ΔGdiss): -6.85 kcal/mol
Dissociation entropy (TΔSdiss): 5.49 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-193019
Monomeric assembly 1 of PDB entry 2h6o coloured by chemically distinct molecules, front view.
Monomeric assembly 1 of PDB entry 2h6o coloured by chemically distinct molecules, side view.
Monomeric assembly 1 of PDB entry 2h6o coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 85%
No. subunits : 1
Symmetry : None
More details
3DComplex & QSbio predictionx
No. subunits : Unclear
Symmetry : Unclear
Evidence : This biological assembly agrees with the prediction of PISA but not of EPPIC

Macromolecules

Major outer envelope glycoprotein gp350
Chain: A
Length: 470 amino acids
Theoretical weight: 50.47 KDa
Source organism: Human gammaherpesvirus 4
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9QP87 (Residues: 1-470; Coverage: 53%)
Pfam:
InterPro: Envelope glycoprotein GP350, N-terminal, A domain, herpervirus
CATH:
Major outer envelope glycoprotein gp350 in PDB entry 2h6o, assembly 1, front view.
Major outer envelope glycoprotein gp350 in PDB entry 2h6o, assembly 1, side view.
Major outer envelope glycoprotein gp350 in PDB entry 2h6o, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q9QP87  
147050100150200250300350400450
 
200400
UniProt
Q9QP87
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Sequence conservation
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