› › Structure analysis

X-ray crystal structure of oxidized human mitochondrial branched chain aminotransferase (hBCATm)

X-ray diffraction
1.8Å resolution
PDB entry 2hhf coloured by chain, front view.
PDB entry 2hhf coloured by chain, side view.
PDB entry 2hhf coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Branched-chain-amino-acid aminotransferase, mitochondrial
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 27155.91 Å2
Buried surface area: 6311.22 Å2
Dissociation area: 2,391.88 Å2
Dissociation energy (ΔGdiss): 21.26 kcal/mol
Dissociation entropy (TΔSdiss): 14.34 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-127453
Hetero dimeric assembly 1 of PDB entry 2hhf coloured by chemically distinct molecules, front view.
Hetero dimeric assembly 1 of PDB entry 2hhf coloured by chemically distinct molecules, side view.
Hetero dimeric assembly 1 of PDB entry 2hhf coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 98%
No. subunits : 2
Symmetry : C2
More details
3DComplex & QSbio predictionx
No. subunits : 2
Symmetry : C2
Evidence : Interface geometry is similar to that of 2coi_1 (59% id)

Macromolecules

Branched-chain-amino-acid aminotransferase, mitochondrial
Chain: A
Length: 365 amino acids
Theoretical weight: 41.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15382 (Residues: 28-392; Coverage: 93%)
Gene names: BCAT2, BCATM, BCT2, ECA40
Pfam: Amino-transferase class IV
InterPro:
CATH:
SCOP: D-aminoacid aminotransferase-like PLP-dependent enzymes
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 2hhf, assembly 1, front view.
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 2hhf, assembly 1, side view.
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 2hhf, assembly 1, top view.
PDBe-KB: UniProt Coverage View: O15382  
Loading Protvista...
Molecule details ›

Search similar proteins

Branched-chain-amino-acid aminotransferase, mitochondrial
Chain: B
Length: 365 amino acids
Theoretical weight: 41.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15382 (Residues: 28-392; Coverage: 93%)
Gene names: BCAT2, BCATM, BCT2, ECA40
Pfam: Amino-transferase class IV
InterPro:
CATH:
SCOP: D-aminoacid aminotransferase-like PLP-dependent enzymes
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 2hhf, assembly 1, front view.
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 2hhf, assembly 1, side view.
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 2hhf, assembly 1, top view.
PDBe-KB: UniProt Coverage View: O15382  
Loading Protvista...
Molecule details ›

Search similar proteins

Quick links