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Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation

Source organisms:
Biochemical function: voltage-gated potassium channel activity
Biological process: potassium ion transport
Cellular component: voltage-gated potassium channel complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF07885
Domain description: Ion channel
Occurring in:
  1. pH-gated potassium channel KcsA
The deposited structure of PDB entry 2ih1 contains 1 copy of Pfam domain PF07885 (Ion channel) in pH-gated potassium channel KcsA. Showing 1 copy in chain C.

PF00520
Domain description: Ion transport protein
Occurring in:
  1. pH-gated potassium channel KcsA
The deposited structure of PDB entry 2ih1 contains 1 copy of Pfam domain PF00520 (Ion transport protein) in pH-gated potassium channel KcsA. Showing 1 copy in chain C.

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
IPR013099
Domain description: Potassium channel domain
Occurring in:
  1. pH-gated potassium channel KcsA
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. FAB Light Chain
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. FAB Light Chain

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. FAB Heavy Chain
  2. FAB Light Chain
The deposited structure of PDB entry 2ih1 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in FAB Heavy Chain. Showing 2 copies in chain A.
The deposited structure of PDB entry 2ih1 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in FAB Light Chain. Showing 2 copies in chain B.
1.10.287.70
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. pH-gated potassium channel KcsA
The deposited structure of PDB entry 2ih1 contains 1 copy of CATH domain 1.10.287.70 (Helix Hairpins) in pH-gated potassium channel KcsA. Showing 1 copy in chain C.

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