Assemblies
Assembly Name:
2-oxoglutarate dehydrogenase E1 component
Multimeric state:
hetero dimer
Accessible surface area:
58321.19 Å2
Buried surface area:
6828.02 Å2
Dissociation area:
2,784.83
Å2
Dissociation energy (ΔGdiss):
25.16
kcal/mol
Dissociation entropy (TΔSdiss):
16.48
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-142717
Macromolecules
Chain: A
Length: 933 amino acids
Theoretical weight: 105.17 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
Length: 933 amino acids
Theoretical weight: 105.17 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0AFG3 (Residues: 1-933; Coverage: 100%)
Pfam:
- 2-oxoglutarate dehydrogenase N-terminus
- Dehydrogenase E1 component
- Transketolase, pyrimidine binding domain
- 2-oxoglutarate dehydrogenase C-terminal
- 2-oxoglutarate dehydrogenase E1 component
- 2-oxoglutarate dehydrogenase E1 component, N-terminal domain
- Thiamin diphosphate-binding fold
- Dehydrogenase, E1 component
- Transketolase-like, pyrimidine-binding domain
- Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
- 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal
Chain: B
Length: 933 amino acids
Theoretical weight: 105.21 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
Length: 933 amino acids
Theoretical weight: 105.21 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P0AFG3 (Residues: 1-933; Coverage: 100%)
Pfam:
- 2-oxoglutarate dehydrogenase N-terminus
- Dehydrogenase E1 component
- Transketolase, pyrimidine binding domain
- 2-oxoglutarate dehydrogenase C-terminal
- 2-oxoglutarate dehydrogenase E1 component
- 2-oxoglutarate dehydrogenase E1 component, N-terminal domain
- Thiamin diphosphate-binding fold
- Dehydrogenase, E1 component
- Transketolase-like, pyrimidine-binding domain
- Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
- 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal
