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Structure of the TycC5-6 PCP-C bidomain of the tyrocidine synthetase TycC

X-ray diffraction
1.85Å resolution
PDB entry 2jgp coloured by chain, front view.
PDB entry 2jgp coloured by chain, side view.
PDB entry 2jgp coloured by chain, top view.
Source organism: Brevibacillus brevis
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Tyrocidine synthase 3
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Multimeric state: monomeric
Accessible surface area: 24230.79 Å2
Buried surface area: 927.18 Å2
Dissociation area: 150.91 Å2
Dissociation energy (ΔGdiss): -5.62 kcal/mol
Dissociation entropy (TΔSdiss): 0.54 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-128244

Macromolecules

Tyrocidine synthase 3
Chain: A
Length: 520 amino acids
Theoretical weight: 58.9 KDa
Source organism: Brevibacillus brevis
Expression system: Escherichia coli
UniProt:
  • Canonical: O30409 (Residues: 5115-5633; Coverage: 8%)
Gene name: tycC
Pfam:
InterPro:
CATH:
Tyrocidine synthase 3 in PDB entry 2jgp, assembly 1, front view.
Tyrocidine synthase 3 in PDB entry 2jgp, assembly 1, side view.
Tyrocidine synthase 3 in PDB entry 2jgp, assembly 1, top view.
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