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P75/LEDGF PWWP Domain

Solution NMR
PDB entry 2m16 coloured by chain, ensemble of 20 models, front view.
PDB entry 2m16 coloured by chain, ensemble of 20 models, side view.
PDB entry 2m16 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: PC4 and SFRS1-interacting protein
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Multimeric state: monomeric
Accessible surface area: 6867.97 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-130985

Macromolecules

PC4 and SFRS1-interacting protein
Chain: A
Length: 97 amino acids
Theoretical weight: 11.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75475 (Residues: 1-93; Coverage: 18%)
Gene names: DFS70, LEDGF, PSIP1, PSIP2
Pfam: PWWP domain
InterPro: PWWP domain
CATH: SH3 type barrels.
PC4 and SFRS1-interacting protein in PDB entry 2m16, assembly 1, front view.
PC4 and SFRS1-interacting protein in PDB entry 2m16, assembly 1, side view.
PC4 and SFRS1-interacting protein in PDB entry 2m16, assembly 1, top view.
PDBe-KB: UniProt Coverage View: O75475  
197102030405060708090
 
50GPGSMTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFS
UniProt
O75475
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Sequence conservation
Molecule details ›

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