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NMR structure of spider toxin- G7W/N24S mutant of TRTX-Hhn2b

Solution NMR
PDB entry 2mxo coloured by chain, ensemble of 20 models, front view.
PDB entry 2mxo coloured by chain, ensemble of 20 models, side view.
PDB entry 2mxo coloured by chain, ensemble of 20 models, top view.
Source organism: Haplopelma hainanum
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Mu-theraphotoxin-Hhn2b 3
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Multimeric state: monomeric
Accessible surface area: 2958.32 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-112434

Macromolecules

Mu-theraphotoxin-Hhn2b 3
Chain: A
Length: 34 amino acids
Theoretical weight: 3.79 KDa
Source organism: Haplopelma hainanum
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: D2Y1X8 (Residues: 49-81; Coverage: 53%)
Pfam: Ion channel inhibitory toxin
InterPro:
Mu-theraphotoxin-Hhn2b 3 in PDB entry 2mxo, assembly 1, front view.
Mu-theraphotoxin-Hhn2b 3 in PDB entry 2mxo, assembly 1, side view.
Mu-theraphotoxin-Hhn2b 3 in PDB entry 2mxo, assembly 1, top view.
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