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Solution structure of RIP2 CARD

Solution NMR
PDB entry 2n7z coloured by chain, ensemble of 10 models, front view.
PDB entry 2n7z coloured by chain, ensemble of 10 models, side view.
PDB entry 2n7z coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Receptor-interacting serine/threonine-protein kinase 2
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Multimeric state: monomeric
Accessible surface area: 7246.14 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-128905

Macromolecules

Receptor-interacting serine/threonine-protein kinase 2
Chain: A
Length: 106 amino acids
Theoretical weight: 12.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43353 (Residues: 434-539; Coverage: 20%)
Gene names: CARDIAK, RICK, RIP2, RIPK2, UNQ277/PRO314/PRO34092
Pfam: Caspase recruitment domain
InterPro:
CATH: Death Domain, Fas
Receptor-interacting serine/threonine-protein kinase 2 in PDB entry 2n7z, assembly 1, front view.
Receptor-interacting serine/threonine-protein kinase 2 in PDB entry 2n7z, assembly 1, side view.
Receptor-interacting serine/threonine-protein kinase 2 in PDB entry 2n7z, assembly 1, top view.
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