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An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance

Source organism: Escherichia coli
Biochemical function: identical protein binding
Biological process: ammonium transmembrane transport
Cellular component: membrane

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00909
Domain description: Ammonium Transporter Family
Occurring in:
  1. Ammonium transporter AmtB
The deposited structure of PDB entry 2npd contains 1 copy of Pfam domain PF00909 (Ammonium Transporter Family) in Ammonium transporter AmtB. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001905
Domain description: Ammonium transporter
Occurring in:
  1. Ammonium transporter AmtB
IPR018047
Domain description: Ammonium transporter, conserved site
Occurring in:
  1. Ammonium transporter AmtB
IPR024041
Domain description: Ammonium transporter AmtB-like domain
Occurring in:
  1. Ammonium transporter AmtB
IPR029020
Domain description: Ammonium/urea transporter
Occurring in:
  1. Ammonium transporter AmtB

Structure domain

CATH CATH domain
1.10.3430.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Ammonium transporter fold
Homology: Ammonium transporter AmtB like domains
Occurring in:
  1. Ammonium transporter AmtB
The deposited structure of PDB entry 2npd contains 1 copy of CATH domain 1.10.3430.10 (Ammonium transporter fold) in Ammonium transporter AmtB. Showing 1 copy in chain A.

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