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Structure of an Enterococcus Faecalis HD Domain Phosphohydrolase

X-ray diffraction
2.55Å resolution
PDB entry 2o6i coloured by chain, front view.
PDB entry 2o6i coloured by chain, side view.
PDB entry 2o6i coloured by chain, top view.
Source organism: Enterococcus faecalis V583
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: HD/PDEase domain-containing protein
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Multimeric state: monomeric
Accessible surface area: 20638.03 Å2
Buried surface area: 500.44 Å2
Dissociation area: 122.63 Å2
Dissociation energy (ΔGdiss): -4.28 kcal/mol
Dissociation entropy (TΔSdiss): 2.38 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-182823
Assembly 2
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Assembly Name: HD/PDEase domain-containing protein
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Multimeric state: monomeric
Accessible surface area: 20726.06 Å2
Buried surface area: 248.0 Å2
Dissociation area: 73.8 Å2
Dissociation energy (ΔGdiss): 12.43 kcal/mol
Dissociation entropy (TΔSdiss): -0.82 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-182823

Macromolecules

HD/PDEase domain-containing protein
Chains: A, B
Length: 480 amino acids
Theoretical weight: 55.89 KDa
Source organism: Enterococcus faecalis V583
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q836G9 (Residues: 1-456; Coverage: 100%)
Gene name: EF_1143
Pfam:
InterPro:
CATH:
SCOP: HD domain
HD/PDEase domain-containing protein in PDB entry 2o6i, assembly 1, front view.
HD/PDEase domain-containing protein in PDB entry 2o6i, assembly 1, side view.
HD/PDEase domain-containing protein in PDB entry 2o6i, assembly 1, top view.
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