› 2opt

X-ray diffraction
2.05Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176083 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 234 amino acids
Theoretical weight: 25.2 KDa
Source organism: Streptomyces coelicolor
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q53901 (Residues: 30-259; Coverage: 89%)
Gene name: actII
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P212121
Unit cell:
a: 55.648Å b: 79.957Å c: 104.027Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.195 0.247
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances.
van Wezel et al. (2011)
12 more

3 mentions without citation

The TetR family of regulators.
Cuthbertson et al. (2013)
2 more