› 2p6p

X-ray diffraction
1.88Å resolution

X-ray crystal structure of C-C bond-forming dTDP-D-Olivose-transferase UrdGT2

Released:
DOI: 10.2210/pdb2p6p/pdb
PDB entry 2p6p coloured by chain, front view.
PDB entry 2p6p coloured by chain, side view.
PDB entry 2p6p coloured by chain, top view.
Source organism: Streptomyces fradiae
Primary publication:
Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin.
Mittler M, Bechthold A, Schulz GE
J Mol Biol 372 67-76 (2007)
PMID: 17640665

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193222 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycosyl transferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 384 amino acids
Theoretical weight: 41.41 KDa
Source organism: Streptomyces fradiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9RPA7 (Residues: 1-365; Coverage: 100%)
Gene name: urdGT2
Sequence domains:
Structure domains: Glycogen Phosphorylase B;

Ligands and Environments

1 bound ligand:
Ligand GOL 7 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 65.872Å b: 78.904Å c: 133.958Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.23
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Natural-product sugar biosynthesis and enzymatic glycodiversification.
Thibodeaux et al. (2008)
11 more

11 mentions without citation

Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.
Kaur et al. (2009)
10 more