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Crystal structure of PH0725 from Pyrococcus horikoshii OT3

X-ray diffraction
2Å resolution
PDB entry 2pci coloured by chain, front view.
PDB entry 2pci coloured by chain, side view.
PDB entry 2pci coloured by chain, top view.
Source organism: Pyrococcus horikoshii OT3
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Diphthine synthase
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Multimeric state: homo dimer
Accessible surface area: 20968.41 Å2
Buried surface area: 5000.82 Å2
Dissociation area: 2,500.41 Å2
Dissociation energy (ΔGdiss): 26.24 kcal/mol
Dissociation entropy (TΔSdiss): 13.9 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-129728

Macromolecules

Diphthine synthase
Chains: A, B
Length: 265 amino acids
Theoretical weight: 29.61 KDa
Source organism: Pyrococcus horikoshii OT3
Expression system: Escherichia coli
UniProt:
  • Canonical: O58456 (Residues: 1-265; Coverage: 100%)
Gene names: PH0725, dph5, dphB
Pfam: Tetrapyrrole (Corrin/Porphyrin) Methylases
InterPro:
CATH:
Diphthine synthase in PDB entry 2pci, assembly 1, front view.
Diphthine synthase in PDB entry 2pci, assembly 1, side view.
Diphthine synthase in PDB entry 2pci, assembly 1, top view.
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