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Crystal Structure of selenomethionine labelled S. aureus IsdE complexed with heme

X-ray diffraction
1.95Å resolution
PDB entry 2q8p coloured by chain, front view.
PDB entry 2q8p coloured by chain, side view.
PDB entry 2q8p coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus N315
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: High-affinity heme uptake system protein IsdE
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-181329

Macromolecules

High-affinity heme uptake system protein IsdE
Chain: A
Length: 260 amino acids
Theoretical weight: 30.11 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q7A652 (Residues: 32-289; Coverage: 95%)
Gene names: SA0980, isdE, sirF
Pfam: Periplasmic binding protein
InterPro:
CATH: Nitrogenase molybdenum iron protein domain
High-affinity heme uptake system protein IsdE in PDB entry 2q8p, assembly 1, front view.
High-affinity heme uptake system protein IsdE in PDB entry 2q8p, assembly 1, side view.
High-affinity heme uptake system protein IsdE in PDB entry 2q8p, assembly 1, top view.
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