GO terms
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR036595
Domain description:
Alpha-macroglobulin, receptor-binding domain superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
2.60.40.1930
Class:
Mainly Beta
Architecture:
Sandwich
Topology:
Immunoglobulin-like
Homology:
Immunoglobulin-like
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 6 copies of CATH domain <span class='highlight'>2.60.40.1930 (Immunoglobulin-like)</span> in <span class='highlight'>Complement C3 beta chain</span>. Showing 3 copies in chain <span class='highlight'>D</span>. The deposited structure of PDB entry 2qki contains 6 copies of CATH domain 2.60.40.1930 (Immunoglobulin-like) in Complement C3 beta chain. Showing 3 copies in chain D.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_1_D_CATH_2.60.40.1930_image-200x200.png)
2.60.40.10
Class:
Mainly Beta
Architecture:
Sandwich
Topology:
Immunoglobulin-like
Homology:
Immunoglobulins
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 2 copies of CATH domain <span class='highlight'>2.60.40.10 (Immunoglobulin-like)</span> in <span class='highlight'>Complement C3 beta chain</span>. Showing 1 copy in chain <span class='highlight'>D</span>. The deposited structure of PDB entry 2qki contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Complement C3 beta chain. Showing 1 copy in chain D.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_1_D_CATH_2.60.40.10_image-200x200.png)
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 2 copies of CATH domain <span class='highlight'>2.60.40.10 (Immunoglobulin-like)</span> in <span class='highlight'>Complement C3c alpha' chain fragment 1</span>. Showing 1 copy in chain <span class='highlight'>E</span>. The deposited structure of PDB entry 2qki contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Complement C3c alpha' chain fragment 1. Showing 1 copy in chain E.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_2_E_CATH_2.60.40.10_image-200x200.png)
2.40.50.120
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 2 copies of CATH domain <span class='highlight'>2.40.50.120 (OB fold (Dihydrolipoamide Acetyltransferase, E2P))</span> in <span class='highlight'>Complement C3c alpha' chain fragment 2</span>. Showing 1 copy in chain <span class='highlight'>F</span>. The deposited structure of PDB entry 2qki contains 2 copies of CATH domain 2.40.50.120 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Complement C3c alpha' chain fragment 2. Showing 1 copy in chain F.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_3_F_CATH_2.40.50.120_image-200x200.png)
2.60.40.690
Class:
Mainly Beta
Architecture:
Sandwich
Topology:
Immunoglobulin-like
Homology:
Alpha-macroglobulin, receptor-binding domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 2 copies of CATH domain <span class='highlight'>2.60.40.690 (Immunoglobulin-like)</span> in <span class='highlight'>Complement C3c alpha' chain fragment 2</span>. Showing 1 copy in chain <span class='highlight'>F</span>. The deposited structure of PDB entry 2qki contains 2 copies of CATH domain 2.60.40.690 (Immunoglobulin-like) in Complement C3c alpha' chain fragment 2. Showing 1 copy in chain F.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_3_F_CATH_2.60.40.690_image-200x200.png)
2.20.130.20
Class:
Mainly Beta
Architecture:
Single Sheet
Topology:
S-adenosyl-L-methionine-dependent methyltransferases
Homology:
S-adenosyl-L-methionine-dependent methyltransferases
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 2 copies of CATH domain <span class='highlight'>2.20.130.20 (S-adenosyl-L-methionine-dependent methyltransferases)</span> in <span class='highlight'>Complement C3c alpha' chain fragment 1</span>. Showing 1 copy in chain <span class='highlight'>E</span>. The deposited structure of PDB entry 2qki contains 2 copies of CATH domain 2.20.130.20 (S-adenosyl-L-methionine-dependent methyltransferases) in Complement C3c alpha' chain fragment 1. Showing 1 copy in chain E.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_2_E_CATH_2.20.130.20_image-200x200.png)
6.20.50.160
Class:
Special
Architecture:
Other non-globular
Topology:
N-terminal domain of TfIIb
Homology:
N-terminal domain of TfIIb
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2qki</span> contains 2 copies of CATH domain <span class='highlight'>6.20.50.160 (N-terminal domain of TfIIb)</span> in <span class='highlight'>Complement C3 beta chain</span>. Showing 1 copy in chain <span class='highlight'>D</span>. The deposited structure of PDB entry 2qki contains 2 copies of CATH domain 6.20.50.160 (N-terminal domain of TfIIb) in Complement C3 beta chain. Showing 1 copy in chain D.](https://www.ebi.ac.uk/pdbe/static/entry/2qki_1_D_CATH_6.20.50.160_image-200x200.png)