Assemblies
Assembly Name:
Complement C3d fragment and peptide
Multimeric state:
hetero tetramer
Accessible surface area:
50777.79 Å2
Buried surface area:
16190.81 Å2
Dissociation area:
686.25
Å2
Dissociation energy (ΔGdiss):
0.94
kcal/mol
Dissociation entropy (TΔSdiss):
8.05
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-133824
Assembly Name:
Complement C3d fragment and peptide
Multimeric state:
hetero tetramer
Accessible surface area:
50014.81 Å2
Buried surface area:
18968.22 Å2
Dissociation area:
710.2
Å2
Dissociation energy (ΔGdiss):
-0.08
kcal/mol
Dissociation entropy (TΔSdiss):
8.04
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-133824
Macromolecules
Chains: A, D
Length: 643 amino acids
Theoretical weight: 71.27 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 643 amino acids
Theoretical weight: 71.27 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 23-665; Coverage: 39%)
Pfam:
- Macroglobulin domain MG1
- MG2 domain
- Macroglobulin domain MG3
- Macroglobulin domain MG4
- Alpha-2-macroglobulin bait region domain
- Complement C3/4/5, macroglobulin domain MG1
- Macroglobulin domain
- Macroglobulin domain MG3
- Immunoglobulin-like fold
- Macroglobulin domain MG4
- Alpha-2-macroglobulin, bait region domain
Chains: B, E
Length: 188 amino acids
Theoretical weight: 21.52 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Alpha-2-macroglobulin family
InterPro:
CATH:
Length: 188 amino acids
Theoretical weight: 21.52 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 749-936; Coverage: 12%)
Pfam: Alpha-2-macroglobulin family
InterPro:
CATH:
Chains: C, F
Length: 343 amino acids
Theoretical weight: 39.54 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 343 amino acids
Theoretical weight: 39.54 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 1321-1663; Coverage: 21%)
Pfam:
- Complement component 3, CUB domain, second segment
- A-macroglobulin receptor binding domain
- UNC-6/NTR/C345C module
- Alpha-macroglobulin, receptor-binding domain superfamily
- Alpha-macroglobulin, receptor-binding
- Tissue inhibitor of metalloproteinases-like, OB-fold
- Complement C3-like, NTR domain
- Netrin domain
- Netrin module, non-TIMP type