› › Structure analysis

Structure of the human SPRY domain-containing SOCS box protein SSB-4

X-ray diffraction
2.2Å resolution
PDB entry 2v24 coloured by chain, front view.
PDB entry 2v24 coloured by chain, side view.
PDB entry 2v24 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: SPRY domain-containing SOCS box protein 4
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 16243.62 Å2
Buried surface area: 2082.38 Å2
Dissociation area: 924 Å2
Dissociation energy (ΔGdiss): -0.67 kcal/mol
Dissociation entropy (TΔSdiss): 12.38 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-188346
Homo dimeric assembly 1 of PDB entry 2v24 coloured by chemically distinct molecules, front view.
Homo dimeric assembly 1 of PDB entry 2v24 coloured by chemically distinct molecules, side view.
Homo dimeric assembly 1 of PDB entry 2v24 coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 89%
No. subunits : 2
Symmetry : C2
More details
3DComplex & QSbio predictionx
No. subunits : Unclear
Symmetry : Unclear
Evidence : This biological assembly agrees with the prediction of PISA but not of EPPIC

Macromolecules

SPRY domain-containing SOCS box protein 4
Chain: A
Length: 208 amino acids
Theoretical weight: 22.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96A44 (Residues: 28-233; Coverage: 76%)
Gene names: SPSB4, SSB4
Pfam: SPRY domain
InterPro:
SPRY domain-containing SOCS box protein 4 in PDB entry 2v24, assembly 1, front view.
SPRY domain-containing SOCS box protein 4 in PDB entry 2v24, assembly 1, side view.
SPRY domain-containing SOCS box protein 4 in PDB entry 2v24, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q96A44  
Loading Protvista...
Molecule details ›

Search similar proteins

Quick links