Assemblies
Assembly Name:
Interleukin-18 and IG-heavy chain and IG-light kappa chain
Multimeric state:
hetero trimer
Accessible surface area:
25746.08 Å2
Buried surface area:
5619.67 Å2
Dissociation area:
2,644.58
Å2
Dissociation energy (ΔGdiss):
15.18
kcal/mol
Dissociation entropy (TΔSdiss):
25.56
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-212017
Macromolecules
Chain: H
Length: 216 amino acids
Theoretical weight: 23.26 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Length: 216 amino acids
Theoretical weight: 23.26 KDa
Source organism: Mus musculus
Expression system: Mus musculus
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin domain subtype
- Immunoglobulin V-set domain
- Immunoglobulin C1-set
Chain: I
Length: 157 amino acids
Theoretical weight: 18.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam: Interleukin-1 / 18
InterPro:
CATH: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 157 amino acids
Theoretical weight: 18.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q14116 (Residues: 37-193; Coverage: 81%)
Pfam: Interleukin-1 / 18
InterPro:
CATH: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Chain: L
Length: 214 amino acids
Theoretical weight: 23.63 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Length: 214 amino acids
Theoretical weight: 23.63 KDa
Source organism: Mus musculus
Expression system: Mus musculus
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin domain subtype
- Immunoglobulin V-set domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
