EC 3.4.21.22: Coagulation factor IXa
Reaction catalysed:
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Alternative Name(s):
- Activated Christmas factor
- Activated blood coagulation factor XI
- Activated blood-coagulation factor IX
- Autoprothrombin II
- Blood platelet cofactor II
- Blood-coagulation factor IXa
- Christmas factor
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Protein families (Pfam)![The deposited structure of PDB entry 2wpj contains 1 copy of Pfam domain PF00089 (Trypsin) in Coagulation factor IXa heavy chain. Showing 1 copy in chain C [auth S].](https://www.ebi.ac.uk/pdbe/static/entry/2wpj_3_S_Pfam_PF00089_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2wpj</span> contains 1 copy of Pfam domain <span class='highlight'>PF00089 (Trypsin)</span> in <span class='highlight'>Coagulation factor IXa heavy chain</span>. Showing 1 copy in chain <span class='highlight'>C [auth S]</span>.")
![The deposited structure of PDB entry 2wpj contains 1 copy of Pfam domain PF14670 (Coagulation Factor Xa inhibitory site) in Coagulation factor IXa light chain. Showing 1 copy in chain A [auth E].](https://www.ebi.ac.uk/pdbe/static/entry/2wpj_1_E_Pfam_PF14670_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2wpj</span> contains 1 copy of Pfam domain <span class='highlight'>PF14670 (Coagulation Factor Xa inhibitory site)</span> in <span class='highlight'>Coagulation factor IXa light chain</span>. Showing 1 copy in chain <span class='highlight'>A [auth E]</span>.")
InterPro annotations
CATH domains![The deposited structure of PDB entry 2wpj contains 2 copies of CATH domain 2.40.10.10 (Thrombin, subunit H) in Coagulation factor IXa heavy chain. Showing 2 copies in chain C [auth S].](https://www.ebi.ac.uk/pdbe/static/entry/2wpj_3_S_CATH_2.40.10.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2wpj</span> contains 2 copies of CATH domain <span class='highlight'>2.40.10.10 (Thrombin, subunit H)</span> in <span class='highlight'>Coagulation factor IXa heavy chain</span>. Showing 2 copies in chain <span class='highlight'>C [auth S]</span>.")
![The deposited structure of PDB entry 2wpj contains 1 copy of CATH domain 2.10.25.10 (Laminin) in Coagulation factor IXa light chain. Showing 1 copy in chain A [auth E].](https://www.ebi.ac.uk/pdbe/static/entry/2wpj_1_E_CATH_2.10.25.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2wpj</span> contains 1 copy of CATH domain <span class='highlight'>2.10.25.10 (Laminin)</span> in <span class='highlight'>Coagulation factor IXa light chain</span>. Showing 1 copy in chain <span class='highlight'>A [auth E]</span>.")