EC 3.2.1.169: Protein O-GlcNAcase
Reaction catalysed:
[Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine + H(2)O = [protein]-L-serine + N-acetyl-D-glucosamine
Systematic name:
[Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase
Alternative Name(s):
- BtGH84
- Glycoside hydrolase O-GlcNAcase
- O-GlcNAc hydrolase
- O-GlcNAcase
- OGA
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence families
Structure domains
CATH domains
1.20.58.460
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology:
Hyaluronidase post-catalytic domain-like
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2wzh</span> contains 1 copy of CATH domain <span class='highlight'>1.20.58.460 (Methane Monooxygenase Hydroxylase; Chain G, domain 1)</span> in <span class='highlight'>O-GlcNAcase BT_4395</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 2wzh contains 1 copy of CATH domain 1.20.58.460 (Methane Monooxygenase Hydroxylase; Chain G, domain 1) in O-GlcNAcase BT_4395. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/2wzh_1_A_CATH_1.20.58.460_image-200x200.png)
3.20.20.80
Class:
Alpha Beta
Architecture:
Alpha-Beta Barrel
Topology:
TIM Barrel
Homology:
Glycosidases
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>2wzh</span> contains 1 copy of CATH domain <span class='highlight'>3.20.20.80 (TIM Barrel)</span> in <span class='highlight'>O-GlcNAcase BT_4395</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 2wzh contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in O-GlcNAcase BT_4395. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/2wzh_1_A_CATH_3.20.20.80_image-200x200.png)