Structure analysis

The structure of the FYR domain

X-ray diffraction
1.6Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 14505.81 Å2
Buried surface area: 2880.75 Å2
Dissociation area: 922.62 Å2
Dissociation energy (ΔGdiss): 4.51 kcal/mol
Dissociation entropy (TΔSdiss): 11.91 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-174891

Macromolecules

Chain: A
Length: 146 amino acids
Theoretical weight: 15.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q3YBR2 (Residues: 179-324; Coverage: 36%)
Gene names: NIAM, TBRG1
Pfam:
InterPro:
CATH: Double Stranded RNA Binding Domain
PDBe-KB: UniProt Coverage View: Q3YBR2  
114620406080100120140
 
50100GRPVFPIGLGGLTVYSLGEIITDRPGFHDESAIYPVGYCSTRIYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPQNAIVSSSADACHAELLRTISTTMGKLMPNLLPAGADFFGFSHPAIHNLIQSCPGARKCINYQWVKFDV
UniProt
Q3YBR2
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Interaction interfaces
Sequence conservation

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