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Crystal Structure of adenosine phosphate-isopentenyltransferase complexed with zinc ion and substrate analog, DMASPP

Source organism: Agrobacterium tumefaciens
Biochemical function: transferase activity
Biological process: cytokinin biosynthetic process
Cellular component: not assigned

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EC 2.5.1.27: Adenylate dimethylallyltransferase (AMP-dependent)

Reaction catalysed:
Prenyl diphosphate + AMP = diphosphate + N(6)-prenyladenosine 5'-phosphate
Systematic name:
Prenyl-diphosphate:AMP prenyltransferase
Alternative Name(s):
  • 2-isopentenyl-diphosphate:AMP Delta(2)-isopentenyltransferase
  • Adenylate isopentenyltransferase
  • Cytokinin synthase
  • Isopentenyltransferase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01745
Domain description: Isopentenyl transferase
Occurring in:
  1. Adenylate dimethylallyltransferase
The deposited structure of PDB entry 2ze7 contains 1 copy of Pfam domain PF01745 (Isopentenyl transferase) in Adenylate dimethylallyltransferase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Adenylate dimethylallyltransferase
IPR002648
Domain description: Adenylate dimethylallyltransferase
Occurring in:
  1. Adenylate dimethylallyltransferase

Structure domains

CATH CATH domains
1.10.287.890
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain
Occurring in:
  1. Adenylate dimethylallyltransferase
The deposited structure of PDB entry 2ze7 contains 1 copy of CATH domain 1.10.287.890 (Helix Hairpins) in Adenylate dimethylallyltransferase. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Adenylate dimethylallyltransferase
The deposited structure of PDB entry 2ze7 contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Adenylate dimethylallyltransferase. Showing 1 copy in chain A.

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