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Structural insight into the membrane insertion of tail-anchored proteins by Get3

Source organism: Saccharomyces cerevisiae
Biochemical function: unfolded protein binding
Biological process: tail-anchored membrane protein insertion into ER membrane
Cellular component: GET complex

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF02374
Domain description: Anion-transporting ATPase
Occurring in:
  1. ATPase GET3
The deposited structure of PDB entry 3a37 contains 2 copies of Pfam domain PF02374 (Anion-transporting ATPase) in ATPase GET3. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR016300
Domain description: Arsenical pump ATPase, ArsA/GET3
Occurring in:
  1. ATPase GET3
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. ATPase GET3
IPR025723
Domain description: Anion-transporting ATPase-like domain
Occurring in:
  1. ATPase GET3
IPR027542
Domain description: Arsenical pump ATPase, ArsA/GET3, eukaryotic
Occurring in:
  1. ATPase GET3

Structure domain

CATH CATH domain
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. ATPase GET3
The deposited structure of PDB entry 3a37 contains 2 copies of CATH domain 3.40.50.300 (Rossmann fold) in ATPase GET3. Showing 1 copy in chain B.

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