Function and Biology

M. jannaschii Nep1 complexed with S-adenosyl-homocysteine

Source organism: Methanocaldococcus jannaschii
Biochemical function: rRNA (pseudouridine) methyltransferase activity
Biological process: rRNA base methylation
Cellular component: not assigned

Sequence family

Pfam Protein family (Pfam)
PF03587
Domain description: EMG1/NEP1 methyltransferase
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1
The deposited structure of PDB entry 3bbd contains 2 copies of Pfam domain PF03587 (EMG1/NEP1 methyltransferase) in Ribosomal RNA small subunit methyltransferase Nep1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR005304
Domain description: Ribosomal biogenesis, methyltransferase, EMG1/NEP1
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1
IPR029028
Domain description: Alpha/beta knot methyltransferases
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1
IPR023503
Domain description: Ribosome biogenesis methyltransferase NEP1, archaea
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1
IPR029026
Domain description: tRNA (guanine-N1-)-methyltransferase, N-terminal
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1

Structure domain

CATH CATH domain
3.40.1280.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Alpha/beta knot
Homology: Alpha/beta knot
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1
The deposited structure of PDB entry 3bbd contains 2 copies of CATH domain 3.40.1280.10 (Alpha/beta knot) in Ribosomal RNA small subunit methyltransferase Nep1. Showing 1 copy in chain A.
SCOP SCOP annotation
159513
Class: Alpha and beta proteins (a/b)
Fold: alpha/beta knot
Superfamily: alpha/beta knot
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase Nep1
The deposited structure of PDB entry 3bbd contains 2 copies of SCOP domain 159513 (EMG1/NEP1-like) in Ribosomal RNA small subunit methyltransferase Nep1. Showing 1 copy in chain A.