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Crystal structure of the complex of Lactoferrin with 6-(Hydroxymethyl)oxane-2,3,4,5-tetrol at 3.49 A resolution

X-ray diffraction
3.49Å resolution
PDB entry 3cr9 coloured by chain, front view.
PDB entry 3cr9 coloured by chain, side view.
PDB entry 3cr9 coloured by chain, top view.
Source organism: Equus caballus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Lactotransferrin
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Multimeric state: monomeric
Accessible surface area: 28876.87 Å2
Buried surface area: 650.01 Å2
Dissociation area: 182.2 Å2
Dissociation energy (ΔGdiss): -3.04 kcal/mol
Dissociation entropy (TΔSdiss): 2.56 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-131272

Macromolecules

Lactotransferrin
Chain: A
Length: 689 amino acids
Theoretical weight: 75.37 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: O77811 (Residues: 7-695; Coverage: 100%)
Gene name: LTF
Pfam: Transferrin
InterPro:
CATH: Periplasmic binding protein-like II
SCOP: Transferrin
Lactotransferrin in PDB entry 3cr9, assembly 1, front view.
Lactotransferrin in PDB entry 3cr9, assembly 1, side view.
Lactotransferrin in PDB entry 3cr9, assembly 1, top view.
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