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Crystal Structure of A20, 2.5 angstrom

X-ray diffraction
2.5Å resolution
PDB entry 3dkb coloured by chain, front view.
PDB entry 3dkb coloured by chain, side view.
PDB entry 3dkb coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: A20p37
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Multimeric state: monomeric
Accessible surface area: 17827.43 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149309
Assembly 2
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Assembly Name: A20p37
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Multimeric state: monomeric
Accessible surface area: 17480.94 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149309
Assembly 3
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Assembly Name: A20p37
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Multimeric state: monomeric
Accessible surface area: 17665.31 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149309
Assembly 4
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Assembly Name: A20p37
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Multimeric state: monomeric
Accessible surface area: 17691.85 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149309
Assembly 5
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Assembly Name: A20p37
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Multimeric state: monomeric
Accessible surface area: 17494.17 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149309
Assembly 6
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Assembly Name: A20p37
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Multimeric state: monomeric
Accessible surface area: 17273.64 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149309

Macromolecules

A20p50
Chains: A, B, C, D, E, F
Length: 390 amino acids
Theoretical weight: 45.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21580 (Residues: 1-370; Coverage: 47%)
Gene names: OTUD7C, TNFAIP3
Pfam: OTU-like cysteine protease
InterPro: OTU domain
A20p50 in PDB entry 3dkb, assembly 1, front view.
A20p50 in PDB entry 3dkb, assembly 1, side view.
A20p50 in PDB entry 3dkb, assembly 1, top view.
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