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Crystal structure of death associated protein kinase in complex with ADP and Mg2+

X-ray diffraction
1.85Å resolution
PDB entry 3f5g coloured by chain, front view.
PDB entry 3f5g coloured by chain, side view.
PDB entry 3f5g coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: DAPK1 - calmodulin complex
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Multimeric state: monomeric
Accessible surface area: 13540.53 Å2
Buried surface area: 933.04 Å2
Dissociation area: 76.07 Å2
Dissociation energy (ΔGdiss): 12.29 kcal/mol
Dissociation entropy (TΔSdiss): -1.46 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-156788

Macromolecules

Death-associated protein kinase 1
Chain: A
Length: 294 amino acids
Theoretical weight: 33.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53355 (Residues: 2-285; Coverage: 20%)
Gene names: DAPK, DAPK1
Pfam: Protein kinase domain
InterPro:
CATH:
Death-associated protein kinase 1 in PDB entry 3f5g, assembly 1, front view.
Death-associated protein kinase 1 in PDB entry 3f5g, assembly 1, side view.
Death-associated protein kinase 1 in PDB entry 3f5g, assembly 1, top view.
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