Structure analysis

X-ray structure of the non covalent swapped form of the Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE

X-ray diffraction
1.94Å resolution
Source organism: Bos taurus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 13747.45 Å2
Buried surface area: 3371.41 Å2
Dissociation area: 1,607.69 Å2
Dissociation energy (ΔGdiss): 11.13 kcal/mol
Dissociation entropy (TΔSdiss): 12.02 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158404

Macromolecules

Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.8 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Pfam: Pancreatic ribonuclease
InterPro:
CATH: Ribonuclease A-like domain

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