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Structure of mouse CD1d in complex with PBS-25

X-ray diffraction
1.7Å resolution
PDB entry 3gmp coloured by chain, front view.
PDB entry 3gmp coloured by chain, side view.
PDB entry 3gmp coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Beta-2-microglobulin and Antigen-presenting glycoprotein CD1d1
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Multimeric state: hetero dimer
Accessible surface area: 19117.93 Å2
Buried surface area: 8237.16 Å2
Dissociation area: 1,444.47 Å2
Dissociation energy (ΔGdiss): 3.37 kcal/mol
Dissociation entropy (TΔSdiss): 12.1 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-135077

Macromolecules

Antigen-presenting glycoprotein CD1d1
Chain: A
Length: 287 amino acids
Theoretical weight: 32.78 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P11609 (Residues: 19-297; Coverage: 88%)
Gene names: Cd1.1, Cd1d1
Pfam:
InterPro:
CATH:
Antigen-presenting glycoprotein CD1d1 in PDB entry 3gmp, assembly 1, front view.
Antigen-presenting glycoprotein CD1d1 in PDB entry 3gmp, assembly 1, side view.
Antigen-presenting glycoprotein CD1d1 in PDB entry 3gmp, assembly 1, top view.
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Beta-2-microglobulin
Chain: B
Length: 99 amino acids
Theoretical weight: 11.66 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P01887 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Beta-2-microglobulin in PDB entry 3gmp, assembly 1, front view.
Beta-2-microglobulin in PDB entry 3gmp, assembly 1, side view.
Beta-2-microglobulin in PDB entry 3gmp, assembly 1, top view.
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