› 3hdi

X-ray diffraction
2.7Å resolution

Crystal structure of Bacillus halodurans metallo peptidase

Released:
DOI: 10.2210/pdb3hdi/pdb
PDB entry 3hdi coloured by chain, front view.
PDB entry 3hdi coloured by chain, side view.
PDB entry 3hdi coloured by chain, top view.
Source organism: Halalkalibacterium halodurans C-125
Primary publication:
Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case.
Aleshin AE, Gramatikova S, Hura GL, Bobkov A, Strongin AY, Stec B, Tainer JA, Liddington RC, Smith JW
Structure 17 1465-75 (2009)
PMID: 19913481

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163619 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Processing protease Chains: A, B
Molecule details ›
Chains: A, B
Length: 421 amino acids
Theoretical weight: 47.59 KDa
Source organism: Alkalihalobacillus halodurans C-125
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KA85 (Residues: 1-413; Coverage: 100%)
Gene name: BH2405
Sequence domains:
Structure domains: Metalloenzyme, LuxS/M16 peptidase-like
Synthetic peptide Chains: C, D
Molecule details ›
Chains: C, D
Length: 17 amino acids
Theoretical weight: 1.23 KDa
Source organism: Halalkalibacterium halodurans C-125
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand CO 2 x CO
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2221
Unit cell:
a: 91.141Å b: 193.981Å c: 125.567Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.269
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

1 review citation

Small-angle X-ray and neutron scattering as a tool for structural systems biology.
Svergun DI. (2010)
15 other articles

4 mentions without citation

Proteasomal Degradation of Zn-Dependent Hdacs: The E3-Ligases Implicated and the Designed Protacs That Enable Degradation.
Márquez-Cantudo et al. (2021)
3 more