Structure analysis

Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3'R,4'R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

X-ray diffraction
2Å resolution
Source organism: Bos taurus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 32246.95 Å2
Buried surface area: 11064.4 Å2
Dissociation area: 68.99 Å2
Dissociation energy (ΔGdiss): 40.76 kcal/mol
Dissociation entropy (TΔSdiss): -0.2 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-151510

Macromolecules

PDBe-KB: UniProt Coverage View: P29473  
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