Structure analysis

Crystal Structure Analysis of a RNA Helicase

X-ray diffraction
2.8Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 21346.48 Å2
Buried surface area: 3138.75 Å2
Dissociation area: 684.73 Å2
Dissociation energy (ΔGdiss): 2.86 kcal/mol
Dissociation entropy (TΔSdiss): 12.74 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-170612

Macromolecules

Chains: A, B
Length: 235 amino acids
Theoretical weight: 26.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08211 (Residues: 329-563; Coverage: 19%)
Gene names: DDX9, DHX9, LKP, NDH2
Pfam: DEAD/DEAH box helicase
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases

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