Function and Biology

Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus

Source organism: Gloeobacter violaceus
Biochemical function: identical protein binding
Biological process: potassium ion transmembrane transport
Cellular component: transmembrane transporter complex

Sequence family

Pfam Protein family (Pfam)
PF02931
Domain description: Neurotransmitter-gated ion-channel ligand binding domain
Occurring in:
  1. Proton-gated ion channel
The deposited structure of PDB entry 3lsv contains 5 copies of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Proton-gated ion channel. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006028
Domain description: Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Occurring in:
  1. Proton-gated ion channel
IPR036734
Domain description: Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Occurring in:
  1. Proton-gated ion channel
IPR038050
Domain description: Neuronal acetylcholine receptor
Occurring in:
  1. Proton-gated ion channel
IPR036719
Domain description: Neurotransmitter-gated ion-channel transmembrane domain superfamily
Occurring in:
  1. Proton-gated ion channel
IPR006202
Domain description: Neurotransmitter-gated ion-channel ligand-binding domain
Occurring in:
  1. Proton-gated ion channel
IPR006201
Domain description: Neurotransmitter-gated ion-channel
Occurring in:
  1. Proton-gated ion channel

Structure domains

CATH CATH domains
1.20.58.390
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology: Neurotransmitter-gated ion-channel transmembrane domain
Occurring in:
  1. Proton-gated ion channel
The deposited structure of PDB entry 3lsv contains 5 copies of CATH domain 1.20.58.390 (Methane Monooxygenase Hydroxylase; Chain G, domain 1) in Proton-gated ion channel. Showing 1 copy in chain A.
2.70.170.10
Class: Mainly Beta
Architecture: Distorted Sandwich
Topology: Acetylcholine Binding Protein; Chain: A,
Homology: Neurotransmitter-gated ion-channel ligand-binding domain
Occurring in:
  1. Proton-gated ion channel
The deposited structure of PDB entry 3lsv contains 5 copies of CATH domain 2.70.170.10 (Acetylcholine Binding Protein; Chain: A,) in Proton-gated ion channel. Showing 1 copy in chain A.