3mj7

X-ray diffraction
2.8Å resolution

Crystal structure of the complex of JAML and Coxsackie and Adenovirus receptor, CAR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-551727 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Junctional adhesion molecule-like Chain: A
Molecule details ›
Chain: A
Length: 268 amino acids
Theoretical weight: 30.65 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q80UL9 (Residues: 21-280; Coverage: 72%)
Gene names: Amica1, Gm638, Jaml
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Coxsackievirus and adenovirus receptor homolog Chain: B
Molecule details ›
Chain: B
Length: 225 amino acids
Theoretical weight: 25.05 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P97792 (Residues: 18-236; Coverage: 63%)
Gene names: Car, Cxadr
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUC
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P3112
Unit cell:
a: 89.865Å b: 89.865Å c: 127.17Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.227 0.276
Expression systems:
  • Drosophila melanogaster
  • Spodoptera frugiperda