Assemblies
Assembly Name:
DNA polymerase eta and DNA
Multimeric state:
hetero trimer
Accessible surface area:
21467.64 Å2
Buried surface area:
6567.59 Å2
Dissociation area:
1,227
Å2
Dissociation energy (ΔGdiss):
24.05
kcal/mol
Dissociation entropy (TΔSdiss):
9.7
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-116585
Macromolecules
Chain: A
Length: 435 amino acids
Theoretical weight: 48.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 435 amino acids
Theoretical weight: 48.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9Y253 (Residues: 1-432; Coverage: 61%)
Pfam:
InterPro:
- Reverse transcriptase/Diguanylate cyclase domain
- DNA/RNA polymerase superfamily
- UmuC domain
- DNA polymerase, Y-family, little finger domain superfamily
- DNA polymerase, Y-family, little finger domain
PDBe-KB: UniProt Coverage View:
Q9Y253
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Name:
DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3')
Representative chains: T
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 11 nucleotides
Theoretical weight: 3.64 KDa
Representative chains: T
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 11 nucleotides
Theoretical weight: 3.64 KDa
Chain B (auth T)
Ligand binding sites
Interaction interfaces
Name:
DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3')
Representative chains: P
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 9 nucleotides
Theoretical weight: 2.72 KDa
Representative chains: P
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 9 nucleotides
Theoretical weight: 2.72 KDa
RSRZ Outlier Chain C (auth P)
Chain C (auth P)
Ligand binding sites
Interaction interfaces