Structure analysis

The structure of Ca2+ Sensor (Case-12)

X-ray diffraction
2.6Å resolution
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 21064.87 Å2
Buried surface area: 263.42 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-143904
Assembly 2
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Multimeric state: monomeric
Accessible surface area: 21173.93 Å2
Buried surface area: 346.65 Å2
Dissociation area: 44.32 Å2
Dissociation energy (ΔGdiss): 12.5 kcal/mol
Dissociation entropy (TΔSdiss): 0.05 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-143904
Assembly 3
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Multimeric state: homo dimer
Accessible surface area: 34826.44 Å2
Buried surface area: 8022.42 Å2
Dissociation area: 3,706.18 Å2
Dissociation energy (ΔGdiss): 52.41 kcal/mol
Dissociation entropy (TΔSdiss): 15.12 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-143905

Macromolecules

Chains: A, B
Length: 415 amino acids
Theoretical weight: 46.49 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P11799 (Residues: 1730-1763; Coverage: 2%)
  • Canonical: P42212 (Residues: 2-170, 191-192; Coverage: 70%)
  • Canonical: P0DP23 (Residues: 23-42, 45-149; Coverage: 84%)
  • nullnullnull
Gene names: CALM, CALM1, CAM, CAM1, GFP, Mylk
Pfam:
InterPro:
CATH:

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