Assemblies
Assembly Name:
polyprotein
Multimeric state:
homo dimer
Accessible surface area:
49456.19 Å2
Buried surface area:
5332.16 Å2
Dissociation area:
1,326.44
Å2
Dissociation energy (ΔGdiss):
6.1
kcal/mol
Dissociation entropy (TΔSdiss):
15.35
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-189300
Macromolecules
Chains: A, B
Length: 666 amino acids
Theoretical weight: 70.87 KDa
Source organism: Hepatitis C virus subtype 1b
Expression system: Escherichia coli
UniProt:
InterPro:
Length: 666 amino acids
Theoretical weight: 70.87 KDa
Source organism: Hepatitis C virus subtype 1b
Expression system: Escherichia coli
UniProt:
- Canonical:
Q99AU2 (Residues: 1029-1657; Coverage: 21%)
InterPro:
- Heat shock protein 70kD, C-terminal domain superfamily
- Hepatitis C virus, NS3 protease
- Peptidase S1, PA clan
- Peptidase S1, PA clan, chymotrypsin-like fold
- P-loop containing nucleoside triphosphate hydrolase
- Helicase superfamily 1/2, ATP-binding domain
- Non-structural protein NS3-like, DEAD box helicase, flavivirus
- Helicase, C-terminal domain-like
