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Mint deletion mutant of heterotetrameric geranyl pyrophosphate synthase in complex with ligands

Source organism: Mentha x piperita
Biochemical function: prenyltransferase activity
Biological process: isoprenoid biosynthetic process
Cellular component: not assigned

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EC 2.5.1.1: Dimethylallyltranstransferase

Reaction catalysed:
Prenyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate
Systematic name:
Prenyl-diphosphate:isopentenyl-diphosphate prenyltranstransferase
Alternative Name(s):
  • (2E,6E)-farnesyl diphosphate synthetase
  • DMAPP:IPP-dimethylallyltransferase
  • Dimethylallyltransferase
  • Diprenyltransferase
  • Geranyl pyrophosphate synthase
  • Geranyl pyrophosphate synthetase
  • Geranyl-diphosphate synthase
  • Prenyltransferase
  • Trans-farnesyl pyrophosphate synthetase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00348
Domain description: Polyprenyl synthetase
Occurring in:
  1. Gpp synthase large subunit
The deposited structure of PDB entry 3oab contains 2 copies of Pfam domain PF00348 (Polyprenyl synthetase) in Geranyl pyrophosphate synthase large subunit. Showing 1 copy in chain D.

InterPro InterPro annotations
IPR008949
Domain description: Isoprenoid synthase domain superfamily
Occurring in:
  1. Gpp synthase large subunit
  2. Geranyl diphosphate synthase small subunit
IPR033749
Domain description: Polyprenyl synthetase, conserved site
Occurring in:
  1. Gpp synthase large subunit
IPR000092
Domain description: Polyprenyl synthetase
Occurring in:
  1. Gpp synthase large subunit

Structure domain

CATH CATH domain
1.10.600.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Farnesyl Diphosphate Synthase
Homology: Farnesyl Diphosphate Synthase
Occurring in:
  1. Gpp synthase large subunit
  2. Geranyl diphosphate synthase small subunit
The deposited structure of PDB entry 3oab contains 2 copies of CATH domain 1.10.600.10 (Farnesyl Diphosphate Synthase) in Geranyl pyrophosphate synthase large subunit. Showing 1 copy in chain D.
The deposited structure of PDB entry 3oab contains 2 copies of CATH domain 1.10.600.10 (Farnesyl Diphosphate Synthase) in Gpp synthase small subunit. Showing 1 copy in chain B.

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