› › Structure analysis

PFKFB3 in complex with Aluminum Tetrafluoride

X-ray diffraction
2.25Å resolution
PDB entry 3qpw coloured by chain, front view.
PDB entry 3qpw coloured by chain, side view.
PDB entry 3qpw coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 39511.52 Å2
Buried surface area: 6520.43 Å2
Dissociation area: 1,651.1 Å2
Dissociation energy (ΔGdiss): -0.33 kcal/mol
Dissociation entropy (TΔSdiss): 14.9 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-172610
Complex Portal ID: CPX-1995
Homo dimeric assembly 1 of PDB entry 3qpw coloured by chemically distinct molecules, front view.
Homo dimeric assembly 1 of PDB entry 3qpw coloured by chemically distinct molecules, side view.
Homo dimeric assembly 1 of PDB entry 3qpw coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 98%
No. subunits : 2
Symmetry : C2
More details
3DComplex & QSbio predictionx
No. subunits : 2
Symmetry : C2
Evidence : Interface geometry is similar to that of 1bif_1 (70% id)

Macromolecules

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Chain: A
Length: 520 amino acids
Theoretical weight: 59.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16875 (Residues: 1-520; Coverage: 100%)
Gene name: PFKFB3
Pfam:
InterPro:
CATH:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 in PDB entry 3qpw, assembly 1, front view.
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 in PDB entry 3qpw, assembly 1, side view.
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 in PDB entry 3qpw, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q16875  
Loading Protvista...
Molecule details ›

Search similar proteins

Quick links