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Structure of neurexin 1 alpha (domains LNS1-LNS6), with splice insert SS3

X-ray diffraction
2.95Å resolution
PDB entry 3r05 coloured by chain, front view.
PDB entry 3r05 coloured by chain, side view.
PDB entry 3r05 coloured by chain, top view.
Source organism: Bos taurus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Neurexin-1
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Multimeric state: monomeric
Accessible surface area: 44931.05 Å2
Buried surface area: 386.1 Å2
Dissociation area: 69.69 Å2
Dissociation energy (ΔGdiss): -4.51 kcal/mol
Dissociation entropy (TΔSdiss): 2.98 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-173308
Assembly 2
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Assembly Name: Neurexin-1
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Multimeric state: monomeric
Accessible surface area: 44921.34 Å2
Buried surface area: 384.43 Å2
Dissociation area: 69.73 Å2
Dissociation energy (ΔGdiss): -4.59 kcal/mol
Dissociation entropy (TΔSdiss): 2.98 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-173308

Macromolecules

Neurexin-1
Chains: A, B
Length: 1254 amino acids
Theoretical weight: 138.51 KDa
Source organism: Bos taurus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q28146 (Residues: 31-1355; Coverage: 83%)
  • Best match: Q28146-6 (Residues: 31-1329)
Gene name: NRXN1
Pfam:
InterPro:
CATH:
Neurexin-1 in PDB entry 3r05, assembly 1, front view.
Neurexin-1 in PDB entry 3r05, assembly 1, side view.
Neurexin-1 in PDB entry 3r05, assembly 1, top view.
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