› › Structure analysis

Crystal structure of human CD38 in complex with compound CZ-46

X-ray diffraction
2.1Å resolution
PDB entry 3roq coloured by chain, front view.
PDB entry 3roq coloured by chain, side view.
PDB entry 3roq coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13172.11 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-151306
Assembly 2
Download    3D Visualisation
Assembly Name: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13029.37 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-151306

Macromolecules

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Chains: A, B
Length: 254 amino acids
Theoretical weight: 29.54 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P28907 (Residues: 45-296; Coverage: 84%)
Gene name: CD38
Pfam: ADP-ribosyl cyclase
InterPro: ADP-ribosyl cyclase (CD38/157)
CATH:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 in PDB entry 3roq, assembly 1, front view.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 in PDB entry 3roq, assembly 1, side view.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 in PDB entry 3roq, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links