› › Structure analysis

Serum paraoxonase-1 by directed evolution at pH 6.5 in complex with 2-hydroxyquinoline

X-ray diffraction
2.19Å resolution
PDB entry 3srg coloured by chain, front view.
PDB entry 3srg coloured by chain, side view.
PDB entry 3srg coloured by chain, top view.
Source organism: synthetic construct
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serum paraoxonase
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Multimeric state: monomeric
Accessible surface area: 13844.73 Å2
Buried surface area: 1411.23 Å2
Dissociation area: 66.77 Å2
Dissociation energy (ΔGdiss): -0.96 kcal/mol
Dissociation entropy (TΔSdiss): 0.59 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-164038

Macromolecules

serum paraoxonase
Chain: A
Length: 355 amino acids
Theoretical weight: 39.6 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
InterPro:
CATH: TolB, C-terminal domain
serum paraoxonase in PDB entry 3srg, assembly 1, front view.
serum paraoxonase in PDB entry 3srg, assembly 1, side view.
serum paraoxonase in PDB entry 3srg, assembly 1, top view.
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