Assemblies
Assembly Name:
Serine protease HTRA1
Multimeric state:
homo trimer
Accessible surface area:
26735.28 Å2
Buried surface area:
8821.42 Å2
Dissociation area:
3,003.33
Å2
Dissociation energy (ΔGdiss):
21.06
kcal/mol
Dissociation entropy (TΔSdiss):
26.1
kcal/mol
Symmetry number:
3
PDBe Complex ID:
PDB-CPX-187740
Macromolecules
Chains: A, B, D
Length: 231 amino acids
Theoretical weight: 25.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam: Trypsin-like peptidase domain
InterPro:
CATH: Trypsin-like serine proteases
Length: 231 amino acids
Theoretical weight: 25.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q92743 (Residues: 161-370; Coverage: 46%)
Pfam: Trypsin-like peptidase domain
InterPro:
CATH: Trypsin-like serine proteases
PDBe-KB: UniProt Coverage View:
Q92743
Q92743
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Interaction interfaces
Sequence conservation